Why a casual hallway conversation at Mayo Clinic could reshape future anti-aging therapies. What if one of the hardest problems in aging research was cracked not by a decades-long program, but by a grad student saying, “What if we tried this?”. That’s exactly what happened at Mayo Clinic. A spontaneous idea led to a powerful … Read more
High intelligence often sabotages health outcomes. Here’s why knowing more doesn’t mean doing better, and what actually works. You’ve read the studies. You understand circadian biology. You know blue light suppresses melatonin and late-night eating disrupts glucose metabolism. You’ve got the Huberman protocols saved. The sleep stack researched. The optimal workout split planned. And yet, … Read more
The science behind cold exposure reveals why some people thrive while others just shiver, and how to find your optimal stress dose. You’ve seen the Instagram posts. Ice baths at sunrise. Cold plunges with motivational captions. Biohackers swearing that freezing water changed their lives. But here’s what nobody talks about: cold exposure works brilliantly for … Read more
A December 2025 FDA panel signals a rare shift in how low testosterone, aging, and treatment access are viewed in the U.S. In December 2025, the U.S. Food and Drug Administration did something it rarely does. It publicly reopened a conversation many regulators had quietly sidelined for years: testosterone decline in men, and whether current … Read more
A large epigenetics study finds higher blood levels of theobromine are tied to a younger biological age, raising new questions about food and longevity. Scientists have spotted an unexpected marker of slower aging hiding in dark chocolate. In a large European study, people with higher blood levels of theobromine, a natural cocoa compound, appeared biologically … Read more
New UK survey data shows most people delay action after noticing dementia symptoms, often because they assume it is “just ageing,” losing precious time for diagnosis and support. Forgetting a name. Losing your train of thought. Struggling to follow a conversation. Many of us shrug these moments off as part of getting older. But according … Read more
A small human study suggests a cheap, non-toxic nutraceutical mix may calm glioblastoma by reducing inflammation and immune evasion, not by killing cells. Glioblastoma is one of the most aggressive cancers known. Even with surgery, chemotherapy, and radiation, median survival is just 15 months. But a new study suggests something unexpected: a simple supplement combination … Read more
A large 2025 German human study challenges the idea that meal timing alone fixes metabolic health. The results don’t kill fasting, but they do change how smart biohackers should use it. Intermittent fasting has been marketed as a metabolic shortcut. Skip breakfast. Compress your eating window. Let biology do the rest. In late 2025, a … Read more
New 2024–2025 human research keeps pointing to the same move: feed your microbes first (fiber), then use probiotics with intent, not vibes. Your digestion can feel perfectly “fine,” yet something still feels off. Low mood that lingers. Energy that never quite rebounds. Skin flares. A vague, puffy sense of inflammation that’s hard to explain but … Read more
A tiny “cleanup system” inside your muscle cells could be the key to feeling younger, recovering faster, and keeping strength for life. Most people think muscle aging is simple. You get older. You lose strength. Workouts feel heavier. Recovery slows. It seems normal. But a new study shows something way more surprising. It reveals that … Read more
A tiny mitochondrial protein just extended lifespan in mice, revealing a surprising new lever for healthy aging. A team in Tokyo has uncovered a mitochondrial mechanism that appears to slow aging at its metabolic roots. Mice engineered to boost a single protein, COX7RP, lived 6.6 percent longer, showed fewer signs of cellular aging, and kept … Read more
Brief, vigorous lifestyle bursts appear to influence inflammation, metabolism and cancer incidence. For people who never set foot in a gym, a surprising new finding changes the conversation about cancer prevention. In a JAMA Oncology study of more than 22,000 nonexercisers, researchers found that just 3 to 4 minutes a day of vigorous “microbursts” built … Read more